1,25(OH)2D is the biologically active form of vitamin D. It has a circulating half-life of approximately 4 hours and circulates at one one-thousandth the concentration of 25(OH)D. Thus, serum 1,25(OH)2D does not reflect vitamin D reserves, and measurement of 1,25(OH)2D is not useful for monitoring the vitamin D status of most patients.
Oct 7, 2022 · Answer From Katherine Zeratsky, R.D., L.D. Vitamin D deficiency — when the level of vitamin D in your body is too low — can cause your bones to become thin, brittle or misshapen. Vitamin D also appears to play a role in insulin production and immune function — and how this relates to chronic disease prevention and cancer — but this is Apr 16, 2020 · To sum up, they estimated that a vitamin D level of 20 ng/mL or higher was adequate for good bone health, and subsequently a level below 20 was considered a vitamin D deficiency. In my practice, and in most, it is not uncommon to see a vitamin D level less than 20. Feb 15, 2017 · The vitamin D metabolites quantified for this study included 25OHD3, 25OHD2, 3-epi-25OHD3, 1α,25(OH) 2 D3 and 24,25(OH) 2 D3. Urine steroid profiling by gas chromatography/mass spectrometry Subjects provided a 24 hour urine collection prior to the study day and on receipt a 30 ml aliquot was transferred to a universal container and stored at 25-Hydroxyvitamin D (25(OH)D 3; calcidiol) is considered the best measure of vitamin D nutritional status because of its long half-life in the circulation of approximately 3 weeks. 25(OH)D 3 is converted in the kidney by 1α-hydroxylase to 1,25(OH) 2 D 3 (calcitriol), the active form of vitamin D, although extrarenal conversion can also occurBecause 1,25-dihydroxyvitamin D is the active form of vitamin D, many practitioners think that measuring 1,25-dihydroxyvitamin D is an accurate means to estimate vitamin D.